Programmable RNA Therapeutics

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Our Company

CircNova, Inc. is a biotechnology company that leverages our unique AI NovaEngine™ to generate, analyze and identify circular RNA for therapeutic development.

Our experts focus on non-coding RNA with many mechanisms of action against undruggable disease targets for major unmet clinical needs.

CircNova is developing a robust IP portfolio for development of circRNA therapeutics.

Our Vision

We are driven by our passion to innovate, discover and lead the development of life-changing RNA based therapies.
We offer partners and patients new solutions to previously undruggable targets that lead to better quality of life.

World's first circRNA 3D structure modeled with deep-learning

Our Technology

Generative Artificial Intelligence has arrived to deliver novel applications in drug discovery, gene therapy, and biotechnology.

AI-guided RNA-folding and active structure prediction coupled with high-throughput RNA synthesis enables revolutionary efficiencies in effective development of therapeutic candidates.

Our AI NovaEngine™ is the first in the world to predict circular RNA structures using deep-learning, allowing unprecedented capability in therapeutic design for "undruggable" diseases, such as Triple-negative Breast Cancer.

Our Leadership

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Crystal Brown, MBA

Chief Executive Officer

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Former CEO, Great Lakes Biologics

Ocuphire Pharma

Gemphire Therapeutics

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Joe Deangelo, PhD

Chief Scientific Officer

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Former CEO, Neochromosome

Former CSO, Apex Bioscience

Great Lakes Biologics

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Steve Schwartz

Chief Technology Officer

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Former CTO, Genomenon

Former CTO, CarCode

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Our Advisors

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Lydia Freddolino, PhD

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Associate Professor, the University of Michigan

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Nils G. Walter, PhD

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Francis S. Collins Collegiate Professor of Chemistry, Biophysics, and Biological Chemistry, University of Michigan

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Vera Hoffman, PhD

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CEO, Reveal Pharmaceuticals

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Danielle Silva, MBA

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SVP, Life Sciences, Banc of California

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